Omega- 3 fatty acids, fish oil, alpha- linolenic acid Interactions. Interactions with Drugs. Omega- 3 may increase the risk of bleeding when taken with drugs that increase the risk of bleeding. Some examples include aspirin, anticoagulants (blood thinners) such as warfarin (Coumadin. Caution is advised when using medications that may also affect blood sugar. People taking drugs for diabetes by mouth or insulin should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary. Alpha-lipoic acid is a fatty acid and an antioxidant. It’s found inside every cell in your body, where it’s essential for. Omega- 3 may cause low blood pressure. Caution is advised in people taking drugs that lower blood pressure. Omega- 3 may also interact with agents that may affect the immune system, agents that may affect the nervous system, agents that may be toxic to the liver, agents that may treat abnormal heart rhythms, agents that may treat arthritis, agents that may treat asthma, agents that may treat gout, agents that may treat heart disorders, agents that may treat retrovirus infections (HIV), antiallergic agents, antiandrogens, anticancer agents, antidepressants (SSRIs), antiestrogens, anti- inflammatories, antipsychotics, aspirin, bone agents, cholesterol- lowering agents, cyclosporine, dexamethasone, eye agents, hormonal agents, paclitaxel, skin agents, and stomach agents. Interactions with Herbs and Dietary Supplements. Omega- 3 may increase the risk of bleeding when taken with herbs and supplements that are believed to increase the risk of bleeding. Multiple cases of bleeding have been reported with the use of Ginkgo biloba, and fewer cases with garlic and saw palmetto. Numerous other agents may theoretically increase the risk of bleeding, although this has not been proven in most cases. Omega- 3 may affect blood sugar levels. Caution is advised when using herbs or supplements that may also affect blood sugar. Blood glucose levels may require monitoring, and doses may need adjustment. Omega- 3 may cause low blood pressure. Caution is advised in people taking herbs or supplements that lower blood pressure. Omega- 3 may also interact with antiallergic agents, antiandrogens, anticancer herbs and supplements, antidepressants (SSRIs), antiestrogens, anti- inflammatories, antioxidants, antipsychotics, bone agents, cholesterol- lowering herbs and supplements, conjugated linoleic acid, evening primrose oil, fat- soluble vitamins, folate, gamma- linolenic acid, glucosamine, herbs and supplements that may affect the immune system, herbs and supplements that may affect the nervous system, herbs and supplements that may be toxic to the liver, herbs and supplements that may treat abnormal heart rhythms, herbs and supplements that may treat arthritis, herbs and supplements that may treat asthma, herbs and supplements that may treat heart disorders, hormonal herbs and supplements, hormone replacement therapy, lycopene, medium- chain triglycerides, phosphatidylserine, phytosterols, policosanol, selenium, skin agents, stomach agents, and vitamin E. Portions of this document last updated: Nov. This evidence- based monograph was prepared by The Natural Standard Research Collaborationwww. Love Your Liver With Alpha Lipoic Acid. News. Target) Even though the liver is not pretty, it is an extremely important organ that has a month- long health observance in October named after it by the American Liver Foundation (www. Liver Awareness Month. Reasons to appreciate our liver abound since this organ does all of the following, and more: saves up energy; makes bile to help break down food; keeps pollution from hurting us; stops cuts from bleeding too long; kills germs; gets rid of toxic chemicals; and helps build muscle. According to the foundation, liver disease affects one in 1. Americans, or about 3. If left untreated, especially over time, inflamed liver tissue begins to scar or become fibrous, a condition known as fibrosis. If fibrosis is not treated or healed, irreversible damage can occur, called cirrhosis; this can lead to liver cancer. If the liver loses most or all of its function, a life- threatening condition called liver failure can result. To complicate matters further, there is also hepatitis C, a disease of the liver caused by the hepatitis C virus, or HCV. Although it is fortunate that 1. HCV are able to successfully fight off the virus within the first six months, sadly most of the patients who are not able to beat the virus wind up developing a long- term, chronic hepatitis C infection. Over 4 million Americans have been infected with hepatitis C and the virus is responsible for 8,0. This is one of the most common reasons for liver transplants. Alpha Lipoic Acid. One nutrient that has been the focus of related research and which shows the greatest promise for liver health has curiously not yet attained the level of popularity enjoyed by milk thistle; it is: alpha lipoic acid. Alpha lipoic acid (or ALA) was discovered by University of Illinois enzymologist Irwin Gunsalus in 1. University of Texas biochemist Lester J. Reed in March 1. 95. It is a natural substance that, according to ALA pioneer Burt Berkson, M. D., in the December 2. Townsend Letter, is the . Bartter, M. D., and other scientists at the National Institutes of Health (NIH). The researchers gave the nutrient to 7. Berkson, recovered full liver function. More recently, in 1. Berkson published three case reports using a triple- antioxidant supplement regimen in patients with liver disease, including chronic hepatitis C infection. After several months of treatment with a combination of alpha lipoic acid, selenium and silymarin, all three patients recovered most or all of their liver function, avoided liver transplantation and went on to live healthy, productive lives free of the symptoms of liver disease. From 2. 00. 6 to 2. Tylenol, Anacin- 3 and Percocet). Since acetaminophen poisoning sends over 5. U. S., these study results are all the more impressive. Additionally, alpha lipoic acid also helps in the areas of nerve health (e. In an industrialized world heavily burdened by pollution and toxic chemicals, alpha lipoic acid has emerged, and rightly so, as a nutritional ray of hope for many. References. American Liver Foundation. October is Liver Awareness Month . September 1. 7, 2. Website accessed September 2. American Liver Foundation. The progression of liver disease . Website accessed September 2. Gormley J. Powerful antioxidant for liver protection and body detoxification: milk thistle. Better Nutrition 5. Berkson BM. Alpha lipoic acid and liver disease. Townsend Letter. December 2. Reed LJ. From lipoic acid to multi- enzyme complexes. Protein Sci 7: 2. Berkson BM. A conservative triple antioxidant approach to the treatment of hepatitis C; combination of alpha lipoic acid (thioctic acid), silymarin and selenium: three case histories. Med Klin (Munich) 9. Suppl 3): 8. 4- 8. Berkson BM et al. The long- term survival of a patient with pancreatic cancer with metastases to the liver after treatment with the intravenous alpha lipoic acid/low- dose naltrexone protocol. Integ Cancer Ther 5(1): 8. D. Reduction of ischemia reperfusion injury after liver resection and hepatic inflow occlusion by alpha lipoic acid in humans. World J Gastroenterol 1. Dudka J. Decrease in NADPH- cytochrome P4. Ann Nutr Metab 5. D. Protection from hepatic ischemia/reperfusion injury and improvement of liver regeneration by alpha lipoic acid. Shock 2. 7(6): 6. D. Protective effects of ischemic preconditioning and application of lipoic acid prior to 9. World J Gastroenterol 1. Anandakumar PP et al. Antioxidant DL- alpha lipoic acid as an attenuator of adriamycin induced hepatotoxicity in rat model. Indian J Exp Biol 4. Abdel- Zaher AO et al. The potential protective role of alpha- lipoic acid against acetaminophen- induced hepatic and renal damage. Toxicology 2. 43(3): 2. CBC News. Use of Tylenol- type pain relief in babies linked to asthma: study. September 1. 9, 2. September 2. 8, 2. Beci. Pharmacological significance of alpha lipoic acid in up to date treatment of diabetic neuropathy. Med Arh 6. 2(1): 4. Pershadsingh HA. Alpha- lipoic acid: physiologic mechanisms and indications for the treatment of metabolic syndrome. Expert Opin Investig Drugs 1. Hager K at al. Alpha- lipoic acid as a new treatment option for Alzheimer's disease: a 4. J Neural Transm Suppl 7. James Gormley is an award- winning health journalist, bestselling author, and member of both the American Society of Journalists and Authors (ASJA) and the Association of Health Care Journalists. He is a senior policy advisor for Citizens for Health and a board member of the National Health Research Institute (NHRI). He writes a regular political and health advocacy column for NOW Foods and his blogs include . Visit him at http: //www. Alpha-lipoic acid is an antioxidant also known as Acetate Replacing Factor, ALA, Biletan, Lipoicin, Thioctan, and many other names. Alpha-lipoic acid is a naturally. Love Your Liver With Alpha Lipoic Acid. Thursday, October 16, 2008 by: James J. Gormley Tags: alpha lipoic acid, health news, Natural News. Mayo Clinic College of Medicine and Science; Mayo Clinic Graduate School of Biomedical Sciences; Mayo Clinic School of Medicine; Mayo Clinic School of Continuous. Alpha lipoic acid can be used to treat many ailments and illnesses. Learn all about alpha lipoic acid and other alternative medicines at HowStuffWorks.
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